Kids are able to heal from injuries so much faster than adults thanks in part to one particular protein. As Anthony shows us, scientists are showing remarkable progress in harnessing that protein into a powerful drug enabling the body to regrow lost tissue.
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Breakthrough discoveries on cellular regeneration seek to turn back the body’s clock
Two groups of scientists at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have made complementary discoveries that break new ground on efforts to turn back the body’s clock on cellular activity, paving the way for a better understanding of stem cells, tissue growth, and regeneration.
Enhances Tissue Repair by Reprogramming Cellular Metabolism
“Regeneration capacity declines with age, but why juvenile organisms show enhanced tissue repair remains unexplained. Lin28a, a highly conserved RNA-binding protein expressed during embryogenesis, plays roles in development, pluripotency, and metabolism.”
Cellular Regeneration Discoveries Seek to Turn Back the Body’s Clock
“Two groups of scientists at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have made complementary discoveries that break new ground on efforts to turn back the body’s clock on cellular activity, paving the way for a better understanding of stem cells, tissue growth and regeneration.”
A network of heterochronic genes including IMP1 regulates temporal changes in stem cell properties
“Stem cell properties change over time to match the changing growth and regeneration demands of tissues. We showed previously that adult forebrain stem cell function declines during aging because of increased expression of let-7 microRNAs, evolutionarily conserved heterochronic genes that reduce HMGA2 expression”
Fountain-of-youth gene repairs tissue damage in adults
“Young animals recover from tissue damage better than adults, and from Charles Darwin’s time until now, scientists have puzzled over why this is the case.”
Watch More:
Why Can’t We Regrow Teeth?
TestTube Wild Card:
Brain Grown in a Lab
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